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Multiple Myeloma: Diagnosis and survival
The International Staging System categorizes multiple myeloma into three stages based on the results of blood concentrations of two proteins: beta-2 microglobulin (ß2-M), a protein that indicates the extent of the disease, and albumin, a protein that is an indicator of overall health.
Stage I
Serum ß2-M less than 3.5 mg/L and a serum albumin less than 3.5 g/dL.
Median survival of 62 months.
Stage II
Defined as not being stage I or III.
Median survival of 44 months.
Stage III
Serum ß2-M of at least 5.5 mg/L.
Median survival of 29 months.